Manufacturer
SANOFI WINTHROP INDUSTRIE
Contents
Amiodarone HCl
Indication
Pulseless ventricular fibrillation or ventricular tachycardia, Supraventricular and ventricular arrhythmias
Instruction
Administer via rapid/slow IV Injection.
Drug interaction
Increased concentration w/ inhibitors of CYP3A4 (e.g. HIV-protease inhibitors, cimetidine). Reduced concentration w/ inducers of CYP3A4 (e.g. rifampicin, phenytoin). May induce bradycardia w/ β-blockers, Ca channel blockers, and other antiarrhythmic drugs. May increase risk of arrhythmia w/ drugs that cause hypomagnesaemia and hypokalaemia (e.g. diuretics, systemic corticosteroids). May increase concentration of ciclosporin, clonazepam, digoxin, flecainide, phenytoin, procainamide, quinidine, simvastatin, and warfarin. May affect drugs that are P-glycoprotein substrates. Potentially Fatal: May cause prolongation of QT interval w/ fluoroquinolones (e.g. moxifloxacin), antipsychotics (e.g. chlorpromazine, thioridazine, fluphenazine), lithium, TCAs (e.g. doxepin, maprotiline, amitriptyline), halofantrine, and terfenadine.
SANOFI WINTHROP INDUSTRIE
Contents
Amiodarone HCl
Indication
Pulseless ventricular fibrillation or ventricular tachycardia, Supraventricular and ventricular arrhythmias
Instruction
Administer via rapid/slow IV Injection.
Drug interaction
Increased concentration w/ inhibitors of CYP3A4 (e.g. HIV-protease inhibitors, cimetidine). Reduced concentration w/ inducers of CYP3A4 (e.g. rifampicin, phenytoin). May induce bradycardia w/ β-blockers, Ca channel blockers, and other antiarrhythmic drugs. May increase risk of arrhythmia w/ drugs that cause hypomagnesaemia and hypokalaemia (e.g. diuretics, systemic corticosteroids). May increase concentration of ciclosporin, clonazepam, digoxin, flecainide, phenytoin, procainamide, quinidine, simvastatin, and warfarin. May affect drugs that are P-glycoprotein substrates. Potentially Fatal: May cause prolongation of QT interval w/ fluoroquinolones (e.g. moxifloxacin), antipsychotics (e.g. chlorpromazine, thioridazine, fluphenazine), lithium, TCAs (e.g. doxepin, maprotiline, amitriptyline), halofantrine, and terfenadine.
Inquiry - Cordarone Inj 150mg (3ml Amp)